Endoglin (CD105) Up-regulation in Pulmonary Microvasculature of Ventilated Preterm Infants
نویسندگان
چکیده
منابع مشابه
Endoglin (CD105) up-regulation in pulmonary microvasculature of ventilated preterm infants.
RATIONALE Preterm infants exposed to mechanical ventilation and oxygen are at risk for bronchopulmonary dysplasia (BPD), a multifactorial chronic lung disorder characterized by arrested alveolar development. Studies have described disruption of microvascular development in BPD, characterized by primitive angioarchitectural patterns reminiscent of the canalicular/saccular stages of lung developm...
متن کاملGrowth of pulmonary microvasculature in ventilated preterm infants.
RATIONALE Density-based morphometric studies have demonstrated decreased capillary density in infants with bronchopulmonary dysplasia (BPD) and in BPD-like animal models, leading to the prevailing view that microvascular development is disrupted in BPD. OBJECTIVE To perform a comprehensive analysis of the early and late effects of ventilation on pulmonary microvascular growth in preterm infan...
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The long-term consequences of extreme prematurity assume more importance as survival rates increase. Pulmonary problems are common immediately after birth and most extremely preterm (EP) infants (<28 weeks' gestation) require respiratory support. Many survivors develop bronchopulmonary dysplasia and some have long-term oxygen dependency, occasionally for years. Their brain has to respond to an ...
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The aim of this study was to determine the effect of surfactant treatment on the number and distribution of inflammatory cells in bronchoalveolar lavage fluid (BALF) from mechanically ventilated preterm infants over the first week of life in relation to the subsequent development of chronic lung disease (CLD). The study included 25 babies who received surfactant on clinical grounds and 29 babie...
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ژورنال
عنوان ژورنال: American Journal of Respiratory and Critical Care Medicine
سال: 2008
ISSN: 1073-449X,1535-4970
DOI: 10.1164/rccm.200608-1240oc